Press "Enter" to skip to content

What Exactly Is Methylsulfonylmethane and How Can It Benefit My Horse?

Last updated on January 4, 2024

What Exactly is Methylsulfonylmethane and How Can It Benefit My Horse?

Methylsulfonylmethane, or MSM, is a highly popular supplement in the equine world. MSM for horses is well known to support healthy joints and is said to reduce the side effects of osteoarthritis. It can be found blended with other joint-friendly supplements or in its pure form to sprinkle directly on feed. But what is it EXACTLY, and what are the benefits (and side effects)? We are big fans of MSM over here at Animal Element, and it’s a main component of 3 of our supplements. So, we decided to do a little “ingredient spotlight” to shine the light on all the benefits this supplement can offer.

The Science Behind MSM

MSM is a sulfur compound that naturally occurs in the body (human and animal) and most plant life. It’s composed of oxygen, sulfur, and carbon and is crucial in producing cartilage and collagen. [1] Sulfur is also an important component in glucosamine, keratin, and cell membrane health. Once in the body, MSM separates and forms into two important amino acids, methionine and cysteine. 

(To read more about what amino acids do, read this blog)

Methylsulfonylmethane has been proven to be an extremely safe supplement, with no known side effects and a very short half-life once in the body. It is used up quickly, the excess being flushed from the horse’s body through urine and feces. Some certain disorders and diseases could be complicated by using MSM, so as always, be sure to consult with your veterinarian before starting a new supplement. [2]

Health Benefits of Methylsulfonylmethane

And boy are there a LOT! Because of its chemical makeup, MSM supports healthy joints, soft tissue regeneration, and reduces scar tissue. It has anti-inflammatory properties, which aid in pain relief, joint mobility, and quick muscle recovery times. This makes it a great supplement to fight the effects of osteoarthritis or old injuries.

Besides being beneficial to joints, MSM is also an antioxidant; boosting the immune system and helping rid the body of toxins by increasing the white blood cell count. It also aids in the production of Vitamins C & E. [3] This allows your horse’s immune system to fight off infections and diseases, keeping your horse healthy and strong.

Since sulfur is important to keratin production, many users of MSM report their horses’ hooves being stronger and healthier, along with improved coat and hair conditions. 

According to, MSM has also “been helpful for horses with Equine Protozoal Myelitis (EPM), back problems, and epiphysitis, which is an inflammation of the growth centers in the joints of young horses.” [4]

MSM in Animal Element Supplements

While we do sell powdered Ultra Pure MSM, we also include it in Foundation Daily Detox, All Creatures Foundation Daily Detox, and Finish 1st Advanced Joint Formula. It’s in so many of our popular supplements because we believe strongly in the benefits of methylsulfonylmethane all across the horse’s body: joints, bones, hooves, coat, and immune system. It naturally reduces pain and swelling, while also repairing soft tissues, cartilage, and nerve cells. Why WOULDN’T we include it in our supplements?! Our goal is to give you research-based, natural, effective, SAFE supplements to bring your horse to their best health and improve their performance. MSM checks all those boxes! So to give it a try, head to our website and place your order now! If you’re still unsure or need more clarification please, call Mark Kaylor directly at 509-301-1798.

All content is intended for informational purposes only. Proudly written for Animal Element by the team at


1 & 3. Durkan, Chris. “Exploring the Benefits of Methylsulfonylmethane for Horses,” April 3, 2023. The Equestrian.

2 & 4. “Equine Drugs & Medications- Methylsulfonylmethane,” June 17, 2014.